Certified Research Suppliers
NovoPro Labs: $103.80/vial (99.65% HPLC purity, TFA-free)
Peptide Institute: cGMP-grade, NMR-verified
Bachem: GLP-compliant with stability data
Experimental Applications
Per published studies:
Obesity mechanisms: Receptor binding kinetics (EC50: GLP-1=0.0643nM)
Metabolic pathways: Glucose uptake assays
Dose-response studies: 2-12mg/week protocols
Handling Best Practices
Reconstitution: Use pH-balanced buffers
Storage: -20°C in aliquoted samples
Dosing Calculations:
Molarity = (mass in g) / (4731.33 g/mol × volume in L)
Inactivation: Autoclave at 121°C for 30 minutes
Publication-Grade Research
Cite key studies:
Jastreboff et al. (NEJM 2023): Phase 2 obesity trial.
Sanyal et al. (Nat Med 2024): MASH efficacy.
Ma et al. (Endocrine 2024): Kidney disease models.
Frequently Asked Questions
Q: Can universities purchase retatrutide?
A: Yes for IRB-approved studies with institutional licenses.
Q: What cell lines respond to retatrutide?
A: HEK-293 with transfected GIP/GLP-1/glucagon receptors show dose-dependent cAMP activation